周扬,理学博士,毕业于中国科学院动物研究所,内蒙古大学“骏马计划”特聘研究员,研究生导师。课题组隶属于内蒙古大学生命科学学院草原家畜生殖调控与繁育国家重点实验室。目前承担多项国家自然科学基金和省部级科研项目,课题组实验技术体系成熟,包括分子生物学和生物化学实验技术、细胞生物学实验技术、生殖生物学相关技术以及生物信息学技术等。研究工作发表在 J Pineal Res(IF=15.2)、PLoS Genet(IF=6.1)、Development(IF=5.9)等国际知名期刊上。担任Journal of Pineal Research、Gene等期刊审稿专家。
课题组的主要研究方向包括:
1、哺乳动物生殖细胞减数分裂启动的调控机制研究;
2、哺乳动物配子发生过程中表观遗传修饰的作用和功能研究;
3、由环境因素介导的哺乳动物生殖受损及获得性遗传的机制研究。
Tel:0471-4995002
Email:zhouyang106 @126.com
学科:动物生殖生物学及生物技术
研究方向: 生殖生物学、表观遗传学、生物信息学
Publications:
(1) Qin Yan#; Zhou Yang#; Shen Zhiming#; Xu Binyang; Chen Min; Li Yaqiong; Chen Min; Behrens Axel; Zhou Jingjing; Qi Xin; Meng Wenxiang; Wang Yaqing; Gao Fei*; WDR62 is involved in spindle assembly by interacting with CEP170 in spermatogenesis, Development, 2019, 146(20): dev174128.
(2) Zhou Yang#; Qin Yan#; Qin Yingying#; Xu Binyang; Guo Ting; Ke Hanni; Chen Min; Zhang Lianjun; Han Feng; Li Yaqiong; Chen Min; Behrens Axel; Wang Yaqing; Xu Zhiheng*; Chen Zi-Jiang*; Gao Fei*; Wdr62 is involved in female meiotic initiation via activating JNK signaling and associated with POI in humans , PLoS Genetics, 2018, 14(8): e1007463.
(3) Zhang Teng#; Zhou Yang#; Li Lan; Zhao Yong; De Felici Massimo; Reiter Russel J; Shen Wei*; Melatonin protects prepuberal testis from deleterious effects of bisphenol A or diethylhexyl phthalate by preserving H3K9 methylation , Journal of Pineal Research, 2018, 65(2): e12497.
(4) Zhang Teng#; Zhou Yang#; Li Li; Wang Zhen Bo; Shen Wei; Schatten Heide; Sun Qing Yuan*; CenpH regulates meiotic G2/M transition by modulating the APC/C-Cdh1-cyclin B1 pathway in oocytes, Development, 2017, 144(2): 305-312.
(5) Han Feng; Liu Chunyi; Zhang Lianjun; Chen Min; Zhou Yang; Qin Yan; Wang Yaqing; Chen Min; Duo Shuguang; Cui Xiuhong; Bao Shilai; Gao Fei*; Globozoospermia and lack of acrosome formation in GM130-deficient mice, Cell Death Dis. 2017 Jan 5;8(1):e2532.
(6) Zhang T#, Zhou Y#, Wang HH, Meng TG, Guo L, Ma XS, Shen W, Schatten H, Sun QY. Spc24 is required for meiotic kinetochore-microtubule attachment and production of euploid eggs, Oncotarget. 2016 Nov 1;7(44):71987-71997.
(7) Zhang T, Zhou Y, Li L, Wang HH, Ma XS, Qian WP, Shen W, Schatten H, Sun QY. SIRT1, 2, 3 protect mouse oocytes from postovulatory aging, Aging (Albany NY). 2016 Apr;8(4):685-96.
(8) Zhang T, Zhou Y, Qi ST, Wang ZB, Qian WP, Ouyang YC, Shen W, Schatten H, Sun QY. Nuf2 is required for chromosome segregation during mouse oocyte meiotic maturation, Cell Cycle. 2015;14(16):2701-10.
(9) Zhou Yang; Zhang Teng; Zhang Qin Kai; Jiang Ying; Xu Deng Gao; Zhang Min; Shen Wei; Pan Qing Jie*; Unstable expression of transgene is associated with the methylation of CAG promoter in the offspring from the same litter of homozygous transgenic mice, Molecular Biology Reports, 2014, 41(8): 5177-5186.
(10) Zhang T, Li L, Qin XS, Zhou Y, Zhang XF, Wang LQ, Massimo De Felici, Chen H, Qin GQ, Shen W. Di-(2-ethylhexyl) Phthalate and Bisphenol A exposure impairs mouse primordial follicle assembly in vitro, Environ Mol Mutagen. 2014 May;55(4):343-53.